Chronology | Current Month | Current Thread | Current Date |
[Year List] [Month List (current year)] | [Date Index] [Thread Index] | [Thread Prev] [Thread Next] | [Date Prev] [Date Next] |
On 2014, Oct 15, , at 00:57, Andreas Bill <Andreas.Bill@csulb.edu> wrote:
PHYSICS COLLOQUIUM---------------------------------------------------------------------------
California State University Long Beach
Monday, October 20, 2014
11:15 am, PH2-110
(Refreshments served at 10:45am in HSCI-224)
require a better surveillance tool and improved vaccine design. Here we
Theoretical Approaches towards HIV Vaccine Designs and Prevention Efforts
Ha Youn Lee
Department of Molecular Microbiology and Immunology
Keck School of Medicine, University of Southern California
Controlling and eradicating an unprecedented HIV/AIDS pandemic will
demonstrate how mathematical and computational tools originating from
statistical physics can be used to advance HIV research. An effective HIV
vaccine must contain antigens that recognize as many HIV peptides as
possible, and the surface morphology of peptide-MHC (pMHC) complexes is one
of the key factors controlling immune response breadth. Our design for
predicting pMHC surface morphology assembles homology-based models and
all-atom molecular dynamics simulations. Once a functional HIV vaccine is
implemented, monitoring HIV incidence, the number of newly infected people,
is necessary to evaluate its efficacy.
signatures embedded in an individual?s HIV sequence population and
Our lab has focused on developing HIV genomic incidence assays utilizing
quantifying the amount of evolution as a fingerprint of infection duration.
Furthermore, mathematical modeling has allowed us to extend our accuracy in
determining infection duration for recently infected individuals. Taken
together, analytical approaches are becoming indispensable components to
medical research
link below
_______________________________________________________________
Colloquium:
Monday, 11:15am, PH2-110
(unless specified otherwise)
Coordinator:
Dr. Andreas Bill, Email: abill@csulb.edu, Tel: +1-562-985-8616
Web site: www.csulb.edu/depts/physics
_______________________________________________________________
_______________________________________________
SCAAPT mailing list
SCAAPT@mailman.csupomona.edu
To change your subscription settings or to unsubscribe, click on the
https://mailman.csupomona.edu/mailman/listinfo/scaapt
Send other questions or comments to the list owner ajm@csupomona.edu
_______________________________________________
Forum for Physics Educators
Phys-l@www.phys-l.org
http://www.phys-l.org/mailman/listinfo/phys-l