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It could be that one does the correct thing given their belief
system, but the result of what they does does not turn out as they
expect. I suppose you could say they made a mistake, but really the
mistake is in their belief of how the world works.
In that sense,
when they are wrong, when they expect something that does not occur,
it is an opportunity to learn.
In the professional scientific world,
one hopes for unexpected results since that provide the entre to new
investigations. My sense of doing science is rather like a business
person who does their day to day work, but are always looking for
that unexpected piece that they can exploit to make more money if you
are in business, or learn new things about the world if you are a
scientist.
Let me make my point a bit clearer. Being wrong does not mean making a mistake necessarily.